TV 00s

Who is left at the altar in the TV series "One Tree Hill"?

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Who became Dan Rather's permanent replacement as anchor for the "CBS Evening News" in 2006?
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On the TV show "Medium", what is the lead character's name?
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In "House", what drug is Dr. Gregory House addicted to?
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Which role did George Clooney originally read for on "ER"?
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